Dr. Brehler worked as a postdoctoral research fellow in the Department of Biomedical Engineering at Johns Hopkins University. His core research interests include active shape models, anatomical landmark identification and atlas-based registration. He is currently working on the development of semi-automatic tools for anatomical landmark annotation and algorithms for automatic landmark identification. He also worked on quantitative assessment of trabecular microarchitecture and automatic joint morphology measurements in volumetric musculoskeletal imaging. His background includes machine learning (classification), intraoperative assessment and visualization of fractures in cone-beam CT data, high resolution microscopy segmentation and cell tracking. He worked at the German Cancer Research Center and obtained his PhD from University of Heidelberg,