Qian Cao Improving High-Resolution CT

July 14, 2016

Graduate student Qian Cao was chosen for the prestigious Howard Hughes Medical Institute International Student Research Fellowship, awarded to just 45 international predoctoral students studying in the United States. The award provides funding through the fifth year of PhD studies.

Qian’s research involves creating new technology for high-resolution CT scanning to detect minute bone changes that signal the early stages of osteoarthritis

“Osteoarthritis,” Cao explains, “is growing steadily more prevalent in the United States as the population ages.” Some estimates suggest that more than 67 million individuals will have osteoarthritis by 2030. “New research is showing that it can be detected in the early stages of progression, before damage to the joint and cartilage begin.”

Cao’s research is under way in the I-STAR Laboratory at Johns Hopkins, where he works under the mentorship of Dr. Wojciech Zbijewski and Dr. Jeffrey Siewerdsen in Biomedical Engineering at Hopkins. “Qian’s work is helping to break the conventional limits of spatial resolution in CT,” says Zbijewski.

(Link to full article) http://engineering.jhu.edu/magazine/2016/06/giving-ct-closer-look/#.V4ffwKI1yQ8

ISTARS Attend The 4th International Conference on Image Formation in X-Ray Computed Tomography

July 8, 2016

I-STARs will present new research in CT Imaging at the 4th International Conference on Image Formation in X Ray Computed  Tomography between July 18th and July 22nd, 2016 at the Welcome Kongresshotel Bamberg, Germany.

Aswin Mathews, PhD presents research related to “Design of  Dual  Multiple  Aperture  Devices  forDynamical Fluence Field Modulated CT” (General Session Tuesday July 19 9:00-9:20)

Alejandro Sisniega, PhD presents his research on “Motion Estimation Using a Penalized Image Sharpness Criterion for Resolution Recovery in Extremities Cone-Beam CT” (CBCT session, Thursday July 21, 15:40-16:00)

Grace Gang, PhD discusses “Task-Based Design of Fluence Field Modulation in CT for Model-Based Iterative Reconstruction” (Iterative Reconstruction Session, Thursday July 21, 11:20-11:40am)

PhD candidate, Steven Tilley shows research on “Modeling Shift-Variant X-Ray Focal Spot Blur for High-Resolution Flat-Panel Cone-Beam CT” (Thursday July 21, 13:20-15:00, Poster Session 3)

Hao Dang provides insight on “Task-Based Regularization Design for Detection of Intracranial Hemorrhage in Cone-Beam CT” (CBCT Session Thursday July 21 16:20-16:40)

I-STAR’s ‘Expanding Horizons’ at the AAPM 2016 Annual Meeting

July 7, 2016

New research from the I-STAR lab will be presented at the AAPM Annual Meeting at the Walter E. Washington Convention Center in Washington DC betewen July 31st and August 4th, 2016.

Qian Cao will discuss his research on “High-Resolution Cone-Beam CT of the Extremities and Cancellous Bone Architecture with a CMOS Detector,” which earned a “Best in Physics” award. (Wednesday, August 3, 2016 at 7:30 – Room: 207A).

Jeff Siewerdsen, PhD discusses the “Advances in Image Registration and Reconstruction for Image-Guided Neurosurgery” (Monday, August 1, 2016 at 2:15pm – Room: 202).

Jennifer Xu presents her research on the “CBCT Head Scanner for Point-Of-Care Imaging of Intracranial Hemorrhage”. (Wednesday, August 3, 2016) at 7:50am -Room: 207A).

Ali Uneri will discuss “Operating Room Quality Assurance (ORQA) for Spine Surgery Using Known-Component 3D-2D Image Registration”  (Wednesday, August 3, 2016 at 8:30am – Room: Ballroom A).

Sarah Ouadah presents the “Correction of Patient Motion in C-Arm Cone-Beam CT Using 3D-2D Registration”(Wednesday, August 3, 2016 at 8:40am – Room: Ballroom A).

Tharindu De Silva, PhD will orate his research on “Registration of Preoperative MRI to Intraoperative Radiographs for Automatic Vertebral Target Localization” (Wednesday, August 3, 2016 at 8:50am – Room: Ballroom A).

Grace Gang, PhD will present her research on “Task-Driven Fluence Field Modulation Design for Model-Based Iterative Reconstruction in CT”  (Thursday, August 4, 2016 at 10:20am –  Room: 207B).

Masters Student, Xiaoxuan Zhang will present her research on “Image-Based Motion Estimation for Plaque Visualization in Coronary Computed Tomography Angiography”  (Thursday, August 4 at 11:50am – Room 206)

Sureerat Reaugamornrat discusses the “Clinical Application of the MIND Demons Algorithm for Symmetric Diffeomorphic Deformable MR-To-CT Image Registration in Spinal Interventions” (Thursday, August 4, 2016 at 11:30am – Room: 206).

Finally, the 2016 Expanding Horizons session includes presentations by Michael Ketcha, Hao Dang, Ali Uneri, Sureerat Reaungamornrat and Dr. Alejandro Sisniega.  (Tuesday, August 2, 2016) 9:30 AM – 11:00 AM Room: ePoster Theater). The session discusses cutting-edge topics from meetings outside the usual sphere of medical physics research, including KDD2016, ASNRMICCAISIAM, the GPU Technology Conference.


Editor’s Pick! spektr 3.0 – New release of x-ray spectrum modeling software

July 6, 2016

The article entitled “SPEKTR 3.0 – A Computational Tool for X-Ray Spectrum Modeling and Analysis” was published in the August issue of Medical Physics, first-authored by Joshua Punnoose, a 3rd-year undergraduate in Biomedical Engineering at Johns Hopkins University. The technical note describes updates and improvements to the MATLAB toolkit for calculation of x-ray spectral characteristics using the improved TASMICS spectral model and a tuning function for users to calculate x-ray spectra matching output for a particular x-ray tube.

In light of this improved spectral model, this Technical Note reports an update to the spektr toolkit with TASMICS as the default method for spectral calculation. The code (referred to as spektr 3.0) also includes a new optimization tool to assist with a common issue faced by TASMIP/TASMICS/spektr users: how to model and match the exposure characteristics of a particular x-ray tube that differs from that in the underlying TASMICS simulation. The code was developed and validated using matlab release 2013b. The spektr 3.0/TASMICS implementation is detailed below, and the code is freely available for download at: http://istar.jhu.edu/downloads/. Video tutorials for the spektr function library, GUI, and optimization tool are available at the same link and at the following YouTube links:

1. https://www.youtube.com/watch?v=84DJndsj9CY,
2. https://www.youtube.com/watch?v=fXenb_LNMKM,
3. https://www.youtube.com/watch?v=Kn588r4arTM.

(Link to paper) http://scitation.aip.org/content/aapm/journal/medphys/43/8/10.1118/1.4955438

I-STARS at CARS: Imaging at the CARS 30th Annual Congress and Exhibition

June 2, 2016

Members of the I-STAR Lab head to Heidelberg for the Computed Assisted Radiology and Surgery Exhibition to present their research in IGS, Image Reconstruction and 3D Image Registration.

Wojtek Zbijewski, PhD, presents “Quantification of bone microarchitecture in ultra-high resolution extremities cone-beam CT with a CMOS detector and compensation of patient motion”  (Thursday, June 23, 2016 Room 2 – 10:00am)

Jennifer Xu’s poster will present the latest work on “Cone-beam CT for point-of-care detection of acute intracranial hemorrhage.”  (Friday June 24th, 8:00-11:15am)

Joseph Goerres, PhD,  discusses “Atlas-based pedicle trajectory prediction for automatic assessment and guidance of screw insertions”  (Surgical/Interventional Informatics, Friday June 24th Room 1 – 10:00am)

Tharindu De Silva, PhD, presents a method to assist spine surgeons in target localization in his talk entitled “LevelCheck” Localization of Spinal Vertebrae in Intraoperative Radiographs from Preoperative MRI” (Friday, June 24th Room 2 – 11:00am)